Frontline Plus For Dogs provides fast, effective and convenient treatment and control of fleas and ticks for dogs and puppies 8 weeks or older.  Frontline Plus remains effective even after bathing, water immersion, or exposure to sunlight.  Frontline comes in a 3 pack, one applicator per month, for a total of 3 months.  The Frontline Plus Orange box is for dogs 11 to 22 Lbs and contains the active ingredients, Fipronil, and (S)-methoprene.  Frontline is a registered trademark of Merial.